Laboratory Diagnosis of Hemoglobinopathies

3/14/2012
12:00 PM to 1:00PM (Americas) Central Time (US & Canada)

Edward C.C. Wong, M.D., Director, Hematology and Peripheral Blood Stem Cell Collection (FACT), Associate Director, Transfusion Medicine, Children’s National Medical Center, Associate Professor of Pediatrics and Pathology, George Washington School of Medicine and Health Sciences, Washington, D.C.

Through the use of informative case studies, this session will describe practical, initial approaches to hemoglobinopathy evaluation. These approaches will highlight the utility of peripheral smear review, RBC and reticulocyte indices, use of capillary zone and gel electrophoresis for hemoglobinopathy evaluation. In addition, the use of HPLC and DNA techniques will be discussed.

Objectives:

  • Understand how RBC and reticulocyte indices can be used to distinguish between thalassemia and iron deficiency
  • Understand the strengths and weaknesses of various diagnostic tests for hemoglobinopathies
  • Determine optimal testing strategies for the evaluation of hemoglobinopathies
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