The Diagnostic Utility of Hematological Parameters to Predict Sepsis

12/10/2014
12:00 PM to 1:00PM (Americas) Central Time (US & Canada)

Alison Woodworth, PhD, DABCC, FACB, Assistant Professor, Pathology, Microbiology and Immunology, Director, Esoteric Chemistry, Vanderbilt University Medical Center, Nashville, TN

Sepsis is a host’s global response to infection. Early diagnosis and treatment by the physician significantly reduces sepsis related mortality. Sepsis is characterized by a profound inflammatory response with up-regulation of white blood cells and organ dysfunction with thrombocytopenia and altered platelets counts. Hematological markers have a role in aiding the clinician in the diagnosis and monitoring of sepsis.

Objectives:

  • Describe the pathobiology of sepsis.
  • Identify hematological abnormalities that occur during sepsis.
  • Discuss the clinical utility of some hematological parameters to predict sepsis.
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