Knowledge for Laboratorians

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    Hematology

    Hematology Case Study - Thrombocytopenia with Elevated IPF

    This patient presents with a mild thrombocytopenia. The XN offers two platelet counting methods:...
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    Hematology

    Hematology Case Study - IG Present

    This is a 76 year old female (see PDF) with a history of chronic myelogenous leukemia (treatment...

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    Hematology

    Hematology Case Study - IG Present #2

    This patient presented with leukocytosis, neutrophilia and basophilia. Immature Granulocytes (IG)...

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    Hematology

    Hematology Case Study - Hemoglobin C Disease

    This sample (pdf), from a patient with Hemoglobin C (Hb C) disease, shows anemia with marked...

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    Hematology

    Hematology Case Study - Howell-Jolly Bodies

    Howell-Jolly bodies, sometimes abbreviated H-J bodies, are DNA remnants that remain in an RBC after...

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    Hematology

    Hematology Case Study - Severe Cold Agglutinin

    This patient is a 51 year old male with a history of multiple myeloma and graft vs. host disease...
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    Hematology

    Hematology Case Study - Diamond-Blackfan Anemia

    This sample (see PDF) was drawn from a 2 year old patient presenting to the pediatrician with...

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    Hematology

    Hematology Case Study - Thalassemia

    The patient (see PDF) is a 37 year old male with a history of thalassemia. The initial analysis of...

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    Hematology

    Hematology Case Study - Micromegakaryocytes

    This newborn (see PDF) presented with leukocytopenia and thrombocytopenia with normal red...

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    Hematology

    Hematology Case Study - Thrombocytopenia

    This 71 year old male (see PDF) presented with markedly decreased platelet count of 8 X10^3/µL....
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    Hematology

    Hematology Case Study - Unmixed Sample

    The sample (see PDF) is initially analyzed in manual mode with no mixing. The probe aspirates...

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    Hematology

    Hematology Case Study - Atypical Lympho

    This sample (see PDF) was from a 79 year old male. A CBC was ordered to rule out anemia.

    The “WBC...

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    Hematology

    Hematology Case Study - Pyruvate Kinase Deficiency

    This patient (see PDF), being seen in the Hematology/Oncology clinic, is known to have pyruvate...

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    Hematology

    Hematology Case Study - Hairy Cell Leukemiase

    Hairy cell leukemia is a B-lymphocyte chronic leukemia where lymphocytes often present with hair...

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    Hematology

    Hematology Case Study - Iron Deficiency Anemia

    Iron deficiency is the most common cause of anemia. Low hemoglobin and hematocrit, red cell indices...

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    Hematology

    Hematology Case Study - High WBC Count with Blasts

    This patient (see PDF) presented with abdominal pain and a CBC showing a high WBC count, mild anemia...

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    Hematology

    Hematology Case Study - WBC Abn Scattergram w-NRBC

    This is an example (see PDF) of false leukocytosis due to the presence of NRBCs. The NRBC result is...
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    Hematology

    Hematology - More than just a CBC: Automated NRBC counts with every result

    Neonatology
    Ideal for high-risk premature infants or pediatric patients. The CBC with NRBC count on...

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    Hematology

    Hematology Overview - Anemia

    Anemia is a global public health issue affecting an estimated one-third of the world’s population,...
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    Hematology

    Hematology - The Use of IG in Infection Management

    Q&A column on use of automated IG versus the manual band count With many laboratories discontinuing...
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    Hematology

    Immature Platelet Fraction Fact Sheet

    What is the Immature Platelet Fraction?

    The Immature Platelet Fraction (IPF) is a parameter available...

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    Hematology

    Immature Granulocyte Fact Sheet

    What are Immature Granulocytes? Immature Granulocytes (IG) are early precursors of granulocytic...
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    Hematology

    Hematology - The New Business Model for Expanded Hematology Paramters - Immature Granulocyte

    The New Business Model for Expanded Hematology Paramters - Immature Granulocyte (IG) These are...
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    Hematology

    Hematology - CPT Codes FAQ for Laboratorians

    Is there a CPT® code or reimbursement available for the automated Immature Granulocyte (IG) count?...
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    Hematology

    Hematology - CAP Q&A Column on Use of IG in Infection Management

    With many laboratories discontinuing manual band counts because of imprecision, Sysmex's Immature...

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    Hematology

    Hematology - Comparing automated vs manual leukocyte differential counts for quantifying the 'left shift' in the blood of neonates

    The presence of a left shift in neonates can be measured via the I/T ratio, which requires a manual...

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    Hematology

    Reticulocyte Hemoglobin Equivalent Fact Sheet

    What is The Reticulocyte Hemoglobin Equivalent?

    The Reticulocyte Hemoglobin Equivalent (RET-He) is a...

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    Hematology

    Hematology - Automated Body Fluid Analysis on Sysmex XN-Series Analyzers

    Find out what scientific experts are saying about the body fluid mode on XN

    The Sysmex XN-Series™...

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    Hematology

    Hematology - XN-20 Hematology Analyzer with WPC Added Value Channel Bibliography

    Find out what scientific experts are saying about the XN-20 The XN-20

    Hematology Analyzer from Sysmex...

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    Hematology

    Hematology Customer Profile - Pomona Valley Hospital Medical Center

    Pomona Valley Hospital Medical Center in Pomona, CA is a nationally recognized community hospital...

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    Hematology

    Hematology White Paper - The Influence of RBC Counting Technology on MCHC Results

    The value-driven laboratory The Influence of RBC Counting Technology on MCHC Results The...
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    Hematology

    Hematology - White Paper Erythrocyte Sedimentation Rate

    Technology, correlation and reference range considerations Introduction The erythrocyte...
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    Hematology

    Customer Profile - Rush University Medical Center

    Immature Granulocytes are Key to Workflow Optimization Faced with the challenge of improving...
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    Hematology

    Automating Body Fluid Analysis for Increased Efficiency

    The association between body fluids and human disease was first popularized around 400 BC when...
  • Variability in Band Reporting
    Hematology

    Significant Variability in the Identification and Reporting of Band Neutrophils by Participants Enrolled in the College of American Pathologists Proficiency Testing Program

    Increased band neutrophils in blood smear differential counts ("bandemia") are entrenched in medi-...

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    Hematology

    And The Band Neutrophil Counts Play On​

    The recent CAP proficiency testing questionnaire was meant to be the coup de grâc Hematology PT...

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    Hemostasis

    Hemostasis - Laboratory Testing of Hemophilia

    Hemophilia is a bleeding disorder caused by the deficiency of either coagulation factor VIII (FVIII)...

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    Hemostasis

    Hemostasis - What is Hemophilia

    Hemophilia is a sex-linked hereditary bleeding disorder caused by the deficiency of either...

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    Hemostasis

    Hemostasis - Activated Partial Thromboplastin Time

    The activated partial thromboplastin time (APTT) is the second most frequently requested coagulation...

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    Hemostasis

    Hemostasis - Prothrombin Time

    The Prothrombin Time (PT) test

    The PT is a baseline screening test for patients with...

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    Principles of Hemostasis, Part I

    The primary principle of hemostasis is to minimize blood loss at sites of vessel injury by forming a...

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    Hemostasis

    Principles of Hemostasis, Part II

    The primary principle of hemostasis is to minimize blood loss at sites of vessel injury by forming a...

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    Urinalysis

    Urinalysis Case Study - Candiduria

    What is Candiduria?

    The genus Candida contains over 200 species, many of which can be found in the...

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    Urinalysis

    Urinalysis Case Study - Decoy Cells

    What are Decoy Cells?

    Decoy cells are urothelial and renal tubular epithelial cells that are infected...

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    Urinalysis

    Urinalysis Case Study - Granular Casts

    What Are Granular Casts?

    Granular casts originate mainly from destruction and degeneration of renal...

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    Urinalysis

    Urinalysis Case Study - Dysmorphic RBCs

    What are Dysmorphic RBCs?

    Red blood cells, also known as erythrocytes, can sometimes be present in...

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    Urinalysis

    Urinalysis Case Study - Hemosiderin

    What is Candiduria?

    The genus Candida contains over 200 species, many of which can be found in the...

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    Urinalysis

    Urinalysis Case Study - Pinworm

    What is Pinworm?

    Enterobius vermicularis, also known as pinworm, is one of the most common...

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    Urinalysis

    Urinalysis Case Study - Cholesterol Crystals

    What are Cholesterol Crystals?

    Cholesterol crystals may be seen in the urine of patients with...

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    Urinalysis

    Urinalysis Case Study - Urothelial Cells

    What are urothelial cells?

    Urothelial cells – also termed “transitional epithelial” cells or...

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    Urinalysis

    Urinalysis Case Study - What is Eosinophiluria

    What is Eosinophiluria?

    Eosinophiluria is a condition that is characterized by the presence of...

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    Urinalysis

    Urinalysis Case Study - Cystinuria

    What is Cystinuria? Cystinuria is an inherited condition characterized by the buildup of cystine in...
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    Urinalysis

    Science of Urinalysis - What is Proteinuria

    What is proteinuria? The function of your kidneys is to filter waste products from your blood and...
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    Urinalysis

    Science of Urinalysis - What is Hematuria

    What is Hematuria Hematuria is defined as the presence of blood in urine, specifically red blood...
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    Urinalysis

    Science of Urinalysis - Bilirubin Crystals

    What are Bilirubin Crystals?

    Bilirubin crystals appear in hepatobiliary diseases and are common in...

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    Urinalysis

    Customer Profile - Morton Hospital

    Morton Hospital in Taunton, MA is a 144-bed acutecare community hospital serving patients and...

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    Flow Cytometry

    Measurable Residual Diseases in Multiple Myeloma

    Validation of a High-Sensitivity 10C Flow Cytometric Measurable Residual Disease (MRD) Assay for...
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    Flow Cytometry

    Customer Profile - Omega Molecular Laboratories

    Omega Molecular Laboratories: Driving Advanced Diagnostics with Sysmex Flow Cytometry to Better...

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    Flow Cytometry

    White Paper - Time Savings with the Sysmex PS-10™ Sample Preparation System

    Time Savings with the Sysmex PS-10™ Sample Preparation System
    Smart automation for a new level of...