Thrombophilia
Sysmex provides high-quality specialty reagents for investigating hypercoagulability in your critical patients.
| Test | Product | Description | Reagent State | Material Number | Kit Size | Tests/Kit |
|---|---|---|---|---|---|---|
| Antithrombin | INNOVANCE® Antithrombin | Chromogenic assay for the quantitative determination of functional antithrombin. The human factor Xa-based reagent has minimal interference with heparin cofactor II and thrombin inhibitors such as hirudin. Ready-to-use liquid reagents. | Liquid MST | 10873856, 10873911, 10873857 | Small Kit, Medium Kit, Large Kit | 150, 300, 450 |
| Antithrombin | Berichrom® Antithrombin III (A) | Chromogenic assay for the detection of hereditary or acquired antithrombin deficiency and monitoring of patients undergoing substitution therapy. The heparin co-factor-independent lyophilized reagent uses bovine thrombin and exhibits no interference with anti-FXa anticoagulants (e.g. Rivaroxaban) | 10873899, 10873898 | Small Kit , Large Kit | 150, 450 | |
| Protein C | Protein C Reagent | Coagulometric reagent used for the quantitative determination of protein C activity. The reagent is suitable for the detection of hereditary or acquired protein C deficiencies. | 10873871 | Kit | 50 | |
| Protein C | Berichrom® Protein C | Chromogenic activity assay. This is used for the detection of hereditary or acquired protein C deficiency types. The assay is also used for the monitoring of substitution therapy with protein C concentrates in congenital protein C deficiency. This assay is less susceptible to interfering substances than a clotting assay. | MST | 10873892, 10873893 | Large Kit, Small Kit | 180, 120 |
| Protein S | Protein S Ac | Coagulometric activity reagent. This is used for the detection of hereditary or acquired protein S deficiencies. | 10873846 | Kit | 60 | |
| Protein S | INNOVANCE® Free PS Ag | This is for the quantitative detection of free protein S. It is a latex-particle enhanced immunoassay utilizing two monoclonal antibodies that have high specificity for free protein S and do not bind to protein S/C4b-binding protein complexes. The high specificity also shows no major interferences, including interferences commonly incurred from rheumatoid factors and heterophilic antibodies. Ready-to-use liquid reagent. | Liquid MST | 10873858 | Kit | 160 |
| Activated Protein C Resistance / Factor V Leiden | ProC® Global | This reagent is a coagulometric screening reagent for the protein C pathway. It provides a determination of the anticoagulatory capacity of the protein C system. This is a heparin insensitive reagent and is useful for screening individuals affected by thrombophilia. This kit is sensitive to deficiencies of factor V Leiden and proteins C and S, certain lupus anticoagulants, and high factor VIII levels. Used in conjunction with Coagulation Factor V Deficient Plasma, ProC Global is a suitable test for the determination of Factor V Leiden. | 10873866 | Kit | 150 | |
| Activated Protein C Resistance / Factor V Leiden | ProC Ac R | This is a dilute Russell’s viper venom test with a sensitivity and specificity of > 99%, which screens for APC resistance due to the presence of factor V Leiden mutation in patient samples. This reagent is insensitive to heparin and is not influenced by high levels of factor VIII. | 10873848 | Kit | 150 | |
| Lupus Anticoagulant | LA 1 Screening Reagent | This reagent contains dilute Russell’s viper venom and low phospholipids for use in the simplified DRVVT as a screening test for the presence of lupus anticoagulants. | MST | 10446063 | 10×2 mL | 180 |
| Lupus Anticoagulant | LA 2 Confirmation Reagent | This reagent is a simplified dilute Russell’s viper venom time rich in phospholipids, aimed for the confirmation of the presence of lupus anticoagulants | MST | 10446064 | 10×1 mL |
MST = Minimal standing time (0-5 min) after reconstitution
For reagent package inserts and other applicable documentation, please visit the Sysmex Customer Resource Center.